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RNAi: [cgc5320]:tbg-1   

[cgc5320]:tbg-1RNAi_reagentyk80h7
MethodRNAi
WormBaseIDWBRNAi00022772
ReferenceWBPaper00005320
Experiment LaboratoryTH
Author (6)
Date26 Mar 2002 00:00:00
StrainWT
Inhibits WB_Predicted_geneF58A4.8 Inferred_automaticallyRNAi_primary
WB_GeneF58A4.8 Inferred_automaticallyRNAi_primary
Gene_targetF58A4.8 WormbaseBLASTBLAST_wormbase_primary
WB_HomolHomol_homolF58A4:RNAi
WB_Uniquely_mapped
RemarkDuring interphase, cytoplasmic MTs were not affected, but assembly of centrosomal asters failed. Centrosomal asters formed as embryos entered mitosis, but spindle assembly never occurred. Centrosomal ZYG-9 was reduced in tbg-1(RNAi) embryos to 30% of wild-type levels. Both the number of astral microtubules and the kinetics of centrosomal microtubule nucleation were compromised in tbg-1(RNAi) embryos.
DeliveryDelivered_byInjection
Results PhenotypeEmb
Phenotype_summary (7)