RNAi: [cgc5320]:tbg-1
[cgc5320]:tbg-1 | RNAi_reagent | yk80h7 | ||||
---|---|---|---|---|---|---|
Method | RNAi | |||||
WormBaseID | WBRNAi00022772 | |||||
Reference | WBPaper00005320 | |||||
Experiment | Laboratory | TH | ||||
Author (6) | ||||||
Date | 26 Mar 2002 00:00:00 | |||||
Strain | WT | |||||
Inhibits | WB_Predicted_gene | F58A4.8 | Inferred_automatically | RNAi_primary | ||
WB_Gene | F58A4.8 | Inferred_automatically | RNAi_primary | |||
Gene_target | F58A4.8 | Wormbase | BLAST | BLAST_wormbase_primary | ||
WB_Homol | Homol_homol | F58A4:RNAi | ||||
WB_Uniquely_mapped | ||||||
Remark | During interphase, cytoplasmic MTs were not affected, but assembly of centrosomal asters failed. Centrosomal asters formed as embryos entered mitosis, but spindle assembly never occurred. Centrosomal ZYG-9 was reduced in tbg-1(RNAi) embryos to 30% of wild-type levels. Both the number of astral microtubules and the kinetics of centrosomal microtubule nucleation were compromised in tbg-1(RNAi) embryos. | |||||
Delivery | Delivered_by | Injection | ||||
Results (2) |