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Gene: C02B8.5   

C02B8.5SMapS_parentSequenceC02B8
ChromosomeX
Identity (5)
Gene_info GO_term GO:0001584 IEA Inferred_automatically
GO:0007186 IEA Inferred_automatically
GO:0016021 IEA Inferred_automatically
Structured_description Provisional_description C02B8.5 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that C02B8.5 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).Paper_evidenceWBPaper00013175
Person_evidenceWBPerson567
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
An extract from flesh fly (Neobellieria bullata) central nervous systems was used to screen cells expressing Drosophila FR; this identified two endogenous peptides, APPQPSDNFIRFamide (Neb-FIRFamide) and pQPSQDFMRFamide (Neb-FMRFamide) as being CG2114 ligands; the Drosophila equivalents of these FMRFamides (DPKQDFMRFamide, TPAEDFMRFamide, SDNFMRFamide, SPKQDFMRFamide, and PDNFMRFamide) activated CG2114.
Concise_descriptionC02B8.5 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that C02B8.5 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
Molecular_info Corresponding_CDSC02B8.5
Corresponding_proteinWP:CE03894
Corresponding_PCR_productsjj_C02B8.5
Corresponding_RNAi_reagent Cenix:157-b3
sjj_C02B8.5
Experimental_info RNAi_result Cenix:157-b3
JA:C02B8.5
WB_RNAi_result JA:C02B8.5
Cenix:157-b3
MethodGene