Gene: C04G2.4
C04G2.4 | SMap | S_parent | Sequence | C04G2 | ||
---|---|---|---|---|---|---|
Chromosome | IV | |||||
Identity (5) | ||||||
Gene_info | Gene_class | msp | ||||
Phenotype | [C.elegansII] NMK. Encodes MSP (16kD); msp-77 cluster. [Ward et al. (1988); BA] | |||||
GO_term | GO:0005198 | IEA | Inferred_automatically | |||
Structured_description | Provisional_description | msp-36 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family comprises of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSP is involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP assembles into fibrous networks that drives movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | Paper_evidence | WBPaper00001023 | ||
WBPaper00002143 | ||||||
WBPaper00004591 | ||||||
WBPaper00005670 | ||||||
Curator_confirmed | WBPerson324 | |||||
Date_last_updated | 22 Mar 2005 00:00:00 | |||||
Concise_description | msp-36 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family comprises of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSP is involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP assembles into fibrous networks that drives movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | |||||
Molecular_info | Corresponding_CDS | C04G2.4 | ||||
Corresponding_protein | WP:CE03853 | |||||
Corresponding_PCR_product | smd_C04G2.4 | |||||
smd_C34F11.4 | ||||||
smd_F32B6.6 | ||||||
smd_F36H12.7 | ||||||
smd_F36H12.7:2 | ||||||
smd_F36H12.8 | ||||||
smd_K07F5.2 | ||||||
smd_K07F5.3 | ||||||
smd_R13H9.2 | ||||||
smd_R13H9.2:2 | ||||||
smd_R13H9.4 | ||||||
smd_T13F2.10 | ||||||
smd_T13F2.11 | ||||||
smd_Y4C6A.c | ||||||
smd_Y59E9_120.c | ||||||
smd_ZK354.1 | ||||||
smd_ZK354.4 | ||||||
smd_ZK354.11 | ||||||
smd_ZK1251.6 | ||||||
sjj_K08F4.8 | ||||||
sjj_R13H9.4 | ||||||
sjj_Y59E9_120.c | ||||||
sjj_ZK354.5 | ||||||
sjj_ZK354.1 | ||||||
sjj_R05F9.13 | ||||||
sjj_F26G1.7 | ||||||
sjj_T13F2.11 | ||||||
sjj_T13F2.10 | ||||||
sjj_K07F5.1 | ||||||
sjj_K07F5.2 | ||||||
sjj_R13H9.2 | ||||||
sjj_ZK1251.6 | ||||||
sjj_Y4C6A.c | ||||||
sjj_C04G2.4 | ||||||
sjj_ZK354.11 | ||||||
sjj_C09B9.6 | ||||||
sjj_C34F11.4 | ||||||
sjj_F32B6.6 | ||||||
sjj_Y59E9_120.c_1 | ||||||
sjj_F58A6.8 | ||||||
sjj_ZK354.4 | ||||||
sjj_F36H12.7 | ||||||
sjj_Y59E9_120.c_2 | ||||||
sjj_K07F5.3 | ||||||
Corresponding_RNAi_reagent (52) | ||||||
Experimental_info | RNAi_result | Cenix:242-d2 | ||||
JA:C04G2.4 | ||||||
[cgc5655]:C04G2.4 | ||||||
WB_RNAi_result (75) | ||||||
Expr_pattern | Expr3417 | |||||
Reference | WBPaper00001023 | |||||
WBPaper00024312 | ||||||
Method | Gene |