Gene: C04G2.4
C04G2.4 | SMap | S_parent | Sequence | C04G2 | ||
---|---|---|---|---|---|---|
Chromosome | IV | |||||
Identity (5) | ||||||
Gene_info | Gene_class | msp | ||||
Phenotype | [C.elegansII] NMK. Encodes MSP (16kD); msp-77 cluster. [Ward et al. (1988); BA] | |||||
GO_term | GO:0005198 | IEA | Inferred_automatically | |||
Structured_description | Provisional_description | msp-36 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family comprises of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSP is involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP assembles into fibrous networks that drives movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | Paper_evidence (4) | |||
Curator_confirmed | WBPerson324 | |||||
Date_last_updated | 22 Mar 2005 00:00:00 | |||||
Concise_description | msp-36 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family comprises of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSP is involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP assembles into fibrous networks that drives movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | |||||
Molecular_info (4) | ||||||
Experimental_info | RNAi_result | Cenix:242-d2 | ||||
JA:C04G2.4 | ||||||
[cgc5655]:C04G2.4 | ||||||
WB_RNAi_result (75) | ||||||
Expr_pattern | Expr3417 | |||||
Reference | WBPaper00001023 | |||||
WBPaper00024312 | ||||||
Method | Gene |