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Gene: C05D11.12 
| C05D11.12 | SMap | S_parent | Sequence | C05D11 | ||
|---|---|---|---|---|---|---|
| Chromosome | III | |||||
| Identity (5) | ||||||
| Gene_info | Gene_class | let | ||||
| Allele | s2447 | Inferred_automatically | From strain object: BC4157 | |||
| s2812 | ||||||
| Phenotype | [Stewart HI ] homozygotes develop into sterile adults | |||||
| [C.elegansII] s2447 : sterile adult. NA1. [BC] | ||||||
| [Stewart HI] Homozygotes arrest development at late larval stage | ||||||
| Strain | BC4157 | |||||
| GO_term | GO:0004174 | IEA | Inferred_automatically | |||
| GO:0006118 | IEA | Inferred_automatically | ||||
| GO:0016491 | IEA | Inferred_automatically | ||||
| Contained_in_operon | CEOP3384 | |||||
| Structured_description | Provisional_description | The let-721 gene encodes an ortholog of the human gene SIMILAR TO ELECTRON-TRANSFERRING-FLAVOPROTEIN DEHYDROGENASE (ETFDH), which when mutated leads to glutaricaciduria type IIC (OMIM:231675). | Paper_evidence | WBPaper00004637 | ||
| Person_evidence | WBPerson567 | |||||
| Curator_confirmed | WBPerson567 | |||||
| Date_last_updated | 17 Jun 2004 00:00:00 | |||||
| Concise_description | The let-721 gene encodes an ortholog of the human gene SIMILAR TO ELECTRON-TRANSFERRING-FLAVOPROTEIN DEHYDROGENASE (ETFDH), which when mutated leads to glutaricaciduria type IIC (OMIM:231675). | |||||
| Molecular_info (5) | ||||||
| Experimental_info | RNAi_result | Cenix:304-g8 | ||||
| JA:C05D11.12 | ||||||
| Simmer:C05D11.12 | ||||||
| TH:304G8 | ||||||
| WB_RNAi_result (5) | ||||||
| Expr_pattern | Expr6401 | |||||
| Reference (13) | ||||||
| Remark | pGV5 is a 6 kb subclone containing the ORFs 12 and 13. let-721 is also rescued by a subclone containing ORF 12 and the left half of C05D11, it must therefore be in ORF 12. | |||||
| The mutation s2833 was previously assigned to let-794. | ||||||
| Method | Gene |
