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Gene: C05D11.3   

C05D11.3SMapS_parentSequenceC05D11
ChromosomeIII
Identity (5)
Gene_info Alleleok776
GO_term GO:0005489 IEA Inferred_automatically
GO:0006118 IEA Inferred_automatically
Contained_in_operonCEOP3376
Structured_description Provisional_descriptionC05D11.3 encodes an ortholog of APACD (ATP binding protein associated with cell differentiation) conserved in eukaryotes; C05D11.3 has a thioredoxin-like domain, probably lacking catalytic activity; mouse APACD is both cytoplasmic and nuclear, often localized to centrosomes and midbody; C05D11.3 is expressed in all developmental stages, preferentially in neurons and vulva; C05D11.3 is required for normal mitotic spindle formation, pronuclear migration and nuclear-centrosome rotation.Paper_evidenceWBPaper00006406
Curator_confirmedWBPerson567
Date_last_updated18 Jul 2005 00:00:00
Concise_descriptionC05D11.3 encodes an ortholog of APACD (ATP binding protein associated with cell differentiation) conserved in eukaryotes; C05D11.3 has a thioredoxin-like domain, probably lacking catalytic activity; mouse APACD is both cytoplasmic and nuclear, often localized to centrosomes and midbody; C05D11.3 is expressed in all developmental stages, preferentially in neurons and vulva; C05D11.3 is required for normal mitotic spindle formation, pronuclear migration and nuclear-centrosome rotation.
Molecular_info Corresponding_CDSC05D11.3
Corresponding_proteinWP:CE01133
KOGKOG1672
Corresponding_PCR_product smd_C05D11.3
sjj_C05D11.3
Corresponding_RNAi_reagent (6)
Experimental_info RNAi_result (6)
WB_RNAi_result (7)
Expr_pattern Expr2872
Expr2873
Expr2874
Expr5784
MethodGene