Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 

Gene: C06G3.7   

C06G3.7SMapS_parentSequenceSUPERLINK_RW4
ChromosomeIV
Identity (5)
Gene_info Gene_classtrxr
GO_term GO:0015036 IEA Inferred_automatically
GO:0006118 IEA Inferred_automatically
GO:0016491 IEA Inferred_automatically
GO:0050660 IEA Inferred_automatically
GO:0005737 IEA Inferred_automatically
GO:0016654 IEA Inferred_automatically
Structured_description Provisional_description (8)
Concise_descriptionC06G3.7 encodes an homolog of the mammalian thioredoxin reductase isozymes TR1 and TR2; like its mammalian homologs, C06G3.7 has a TGA-encoded C-terminal penultimate selenocysteine (Sec) residue; labelling of C. elegans with selenium-75 demonstrates that TR-Se is the major naturally occurring selenoprotein in C. elegans, and computational analysis indicates that it is probably the only selenoprotein encoded by the genome; the 3'-untranslated region of this gene contains a selenocysteine insertion sequence that is functional in mammalian cell culture; by phylogenetic profiling, C06G3.7 protein is predicted to be mitochondrial.
Molecular_info (6)
Experimental_info RNAi_resultCenix:39-b9
WB_RNAi_resultCenix:39-b9
MethodGene