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Gene: C09D8.1   

C09D8.1SMapS_parentSequenceSUPERLINK_CB_II
ChromosomeII
Identity (5)
Gene_info Gene_classptp
Allele (10)
Phenotype (2)
Strain CZ540
RB633
GO_term (8)
Structured_description Provisional_descriptionptp-3 encodes a receptor-like tyrosine phosphatase orthologous to the LAR (Leukocyte Common Antigen Related, OMIM:179590) subfamily of receptor-like tyrosine phosphatases that contain extracellular immunoglobulin-like and fibronectin type III domains and have been implicated in linking cell adhesion to intracellular phosphotyrosine levels; PTP-3 plays a role in gastrulation and epidermal development and functions partly redundantly with the VAB-1 Eph receptor and ephrins VAB-2 and EFN-4 to regulate embryonic morphogenesis; PTP-3 is expressed in many tissues during early embryogenesis, but expression later becomes localized to neuronal processes and epithelial adherens junctions. Paper_evidence WBPaper00005259
WBPaper00005631
Person_evidenceWBPerson1843
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Concise_descriptionptp-3 encodes a receptor-like tyrosine phosphatase orthologous to the LAR (Leukocyte Common Antigen Related, OMIM:179590) subfamily of receptor-like tyrosine phosphatases that contain extracellular immunoglobulin-like and fibronectin type III domains and have been implicated in linking cell adhesion to intracellular phosphotyrosine levels; PTP-3 plays a role in gastrulation and epidermal development and functions partly redundantly with the VAB-1 Eph receptor and ephrins VAB-2 and EFN-4 to regulate embryonic morphogenesis; PTP-3 is expressed in many tissues during early embryogenesis, but expression later becomes localized to neuronal processes and epithelial adherens junctions.
Molecular_info (6)
Experimental_info (5)
Reference (14)
Remark (2)
MethodGene