C09H6.2 | SMap | S_parent | Sequence | C09H6
|
| Chromosome | I |
|
Identity (5)
|
|
Gene_info
| Gene_class | lin
|
| | Reference_allele | e1439
|
| |
Allele
| e1438
|
Inferred_automatically
| From strain object: BW538 |
| | | | | From strain object: BW589 |
| | | | | From strain object: BW635 |
| | | e1439
|
Inferred_automatically
| From strain object: CB1439 |
| | | | | From strain object: MT2351 |
| | | | | From strain object: RW1482 |
| | | n299
|
| | | n1299
| Inferred_automatically | From strain object: MT2981 |
| | | n1326
| Inferred_automatically | From strain object: MT2981 |
| | | n1386
| Inferred_automatically | From strain object: MT3228 |
| | | n1387
| Inferred_automatically | From strain object: MT3229 |
| | | n1390
|
Inferred_automatically
| From strain object: MT3232 |
| | | | | From strain object: VT592 |
| | | n1402
| Inferred_automatically | From strain object: MT3252 |
| | | n1508
|
| | | n1511
| Inferred_automatically | From strain object: MT3632 |
| | | n1638
|
| | | n1759
| Inferred_automatically | From strain object: MT4006 |
| | | n1853
| Inferred_automatically | From strain object: MT4351 |
| | | sy217
|
| | | uCE1-957
|
| | | uCE1-958
|
| |
Phenotype
| e1439 : adult hermaphrodite vulvaless (penetrance 95%) HME2; adult male wildtype ME3. Similar phenotype in e1439/Df. NA3 (e1438 n299). |
| | | See also e1438, e1439, n299, n1299, n1329 |
| | | [C.elegansII] e1439 : adult hermaphrodite vulvaless (penetrance 95%) HME2; adult male wildtype ME3. Similar phenotype in e1439/Df. OA>5; e1438, n299, n1299, n1329, n1638amb, etc.C loned: encodes predicted 407aa novel protein;antibody staining indicates ubiquitous,cytoplasmic. [Kim and Horvitz 1990; MT; SD] |
| |
Strain (15)
|
| |
GO_term (13)
|
| |
Structured_description
| Provisional_description | The lin-10 gene encodes a PDZ and PTB domain-containing protein that is homologous to mammalian Munc interacting proteins (Mint1, OMIM:602414) and is required for polarized protein localization; LIN-10 is required for proper localization of the LET-23 EGF receptor to the basolateral membrane of the vulval precursor cells and for proper postsynaptic localization of GLR-1, an AMPA-type glutamate receptor in interneurons; LIN-10 is detected in the cytoplasm, membrane, and at particularly high levels in the Golgi. |
Paper_evidence
| WBPaper00003214
|
| | | | | | WBPaper00003566
|
| | | | | | WBPaper00005047
|
| | | | | | WBPaper00005666
|
| | | | | Person_evidence | WBPerson1843
|
| | | | | Curator_confirmed | WBPerson1843
|
| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | Concise_description | The lin-10 gene encodes a PDZ and PTB domain-containing protein that is homologous to mammalian Munc interacting proteins (Mint1, OMIM:602414) and is required for polarized protein localization; LIN-10 is required for proper localization of the LET-23 EGF receptor to the basolateral membrane of the vulval precursor cells and for proper postsynaptic localization of GLR-1, an AMPA-type glutamate receptor in interneurons; LIN-10 is detected in the cytoplasm, membrane, and at particularly high levels in the Golgi. |
|
Molecular_info (7)
|
|
Experimental_info
|
RNAi_result
| Cenix:71-e2
|
| | | JA:C09H6.2
|
| |
WB_RNAi_result
| SA:yk297c2
|
| | | JA:C09H6.2
|
| | | Cenix:71-e2
|
| |
Expr_pattern
| Expr1282
|
| | | Expr1385
|
| | | Expr5703
|
| | | Expr5704
|
| |
Interaction (12)
|
|
Reference (128)
|
| Remark | lin-10 is NOT T01G9.2 [jah 8/99] |
| Method | Gene
|