Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 

Gene: C09H6.2   

C09H6.2SMapS_parentSequenceC09H6
ChromosomeI
Identity (5)
Gene_info Gene_classlin
Reference_allelee1439
Allele (17)
Phenotype e1439 : adult hermaphrodite vulvaless (penetrance 95%) HME2; adult male wildtype ME3. Similar phenotype in e1439/Df. NA3 (e1438 n299).
See also e1438, e1439, n299, n1299, n1329
[C.elegansII] e1439 : adult hermaphrodite vulvaless (penetrance 95%) HME2; adult male wildtype ME3. Similar phenotype in e1439/Df. OA>5; e1438, n299, n1299, n1329, n1638amb, etc.C loned: encodes predicted 407aa novel protein;antibody staining indicates ubiquitous,cytoplasmic. [Kim and Horvitz 1990; MT; SD]
Strain (15)
GO_term GO:0008105 IDA Paper_evidence WBPaper00003214
WBPaper00003566
Curator_confirmedWBPerson1843
GO:0007270 IMP Paper_evidenceWBPaper00003214
Curator_confirmedWBPerson1843
GO:0040026 IMP Paper_evidenceWBPaper00000762
Curator_confirmedWBPerson1843
GO:0050975 IMP Paper_evidenceWBPaper00003214
Curator_confirmedWBPerson1843
GO:0043113 ISS Paper_evidenceWBPaper00003566
Curator_confirmedWBPerson1843
GO:0005737 IDA Paper_evidenceWBPaper00003566
Curator_confirmedWBPerson1843
GO:0005886 IDA Paper_evidenceWBPaper00003566
Curator_confirmedWBPerson1843
GO:0000138 IDA Paper_evidenceWBPaper00003566
Curator_confirmedWBPerson1843
GO:0043005 IDA Paper_evidenceWBPaper00003566
Curator_confirmedWBPerson1843
GO:0043025 IDA Paper_evidenceWBPaper00003566
Curator_confirmedWBPerson1843
GO:0030140 IDA Paper_evidenceWBPaper00003566
Curator_confirmedWBPerson1843
GO:0001784 ISS Paper_evidenceWBPaper00003566
Curator_confirmedWBPerson1843
GO:0005515 IDA Paper_evidenceWBPaper00003215
Curator_confirmedWBPerson1843
IEA Inferred_automatically
Structured_description Provisional_descriptionThe lin-10 gene encodes a PDZ and PTB domain-containing protein that is homologous to mammalian Munc interacting proteins (Mint1, OMIM:602414) and is required for polarized protein localization; LIN-10 is required for proper localization of the LET-23 EGF receptor to the basolateral membrane of the vulval precursor cells and for proper postsynaptic localization of GLR-1, an AMPA-type glutamate receptor in interneurons; LIN-10 is detected in the cytoplasm, membrane, and at particularly high levels in the Golgi. Paper_evidence WBPaper00003214
WBPaper00003566
WBPaper00005047
WBPaper00005666
Person_evidenceWBPerson1843
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Concise_descriptionThe lin-10 gene encodes a PDZ and PTB domain-containing protein that is homologous to mammalian Munc interacting proteins (Mint1, OMIM:602414) and is required for polarized protein localization; LIN-10 is required for proper localization of the LET-23 EGF receptor to the basolateral membrane of the vulval precursor cells and for proper postsynaptic localization of GLR-1, an AMPA-type glutamate receptor in interneurons; LIN-10 is detected in the cytoplasm, membrane, and at particularly high levels in the Golgi.
Molecular_info (7)
Experimental_info RNAi_result Cenix:71-e2
JA:C09H6.2
WB_RNAi_result SA:yk297c2
JA:C09H6.2
Cenix:71-e2
Expr_pattern Expr1282
Expr1385
Expr5703
Expr5704
Interaction (12)
Reference (128)
Remarklin-10 is NOT T01G9.2 [jah 8/99]
MethodGene