C33F10.9 | SMap | S_parent | Sequence | C33F10
|
| Chromosome | II |
|
Identity (5)
|
|
Gene_info
| Gene_class | msp
|
| | Phenotype | [C.elegansII] NMK. Encodes MSP (16kD); msp-3 cluster. [Ward et al. (1988); BA] |
| | GO_term | GO:0005198
| IEA
| Inferred_automatically |
| |
Structured_description
| Provisional_description | msp-40 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Paper_evidence
| WBPaper00001023
|
| | | | | | WBPaper00002143
|
| | | | | | WBPaper00004591
|
| | | | | | WBPaper00005670
|
| | | | | Curator_confirmed | WBPerson324
|
| | | | | Date_last_updated | 31 Mar 2005 00:00:00 |
| | | Concise_description | msp-40 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
|
Molecular_info
| Corresponding_CDS | C33F10.9
|
| | Corresponding_protein | WP:CE02806
|
| |
Corresponding_PCR_product
| smd_C33F10.9
|
| | | smd_F32B6.6
|
| | | smd_R05F9.3
|
| | | smd_T13F2.10
|
| | | smd_ZK546.3
|
| | | smd_ZK546.6
|
| | | sjj_C33F10.9
|
| | | sjj_ZK546.6
|
| | | sjj_R05F9.13
|
| | | sjj_F26G1.7
|
| | | sjj_R05F9.8
|
| | | sjj_T13F2.10
|
| | | sjj_R05F9.5
|
| | | sjj_F09C12.7
|
| | | sjj_F32B6.6
|
| | | sjj_R05F9.3
|
| | | sjj_ZK546.3
|
| | | sjj_F58A6.8
|
| |
Corresponding_RNAi_reagent (23)
|
|
Experimental_info
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RNAi_result
| Cenix:203-f3
|
| | | JA:C33F10.9
|
| |
WB_RNAi_result (81)
|
| | Expr_pattern | Expr3417
|
|
Reference
| WBPaper00001023
|
| | WBPaper00015440
|
| | WBPaper00024312
|
| | WBPaper00025088
|
| Method | Gene
|