RNAiDB Tree View

Gene: C34F11.4

C34F11.4	SMap	S_parent	Sequence	C34F11
	Chromosome	II
	Identity	Version	1
		Name	CGC_name	msp-50	Person_evidence	WBPerson680
			Sequence_name	C34F11.4
			Molecular_name	C34F11.4
				WP:CE02806
				CE02806
			Other_name	NM_062571	Inferred_automatically
					Date_last_updated	15 Apr 2005 00:00:00	WS142

			Public_name	msp-50
			Synonym (5)
			WBGeneID	WBGene00003443
		Species	Caenorhabditis elegans
		History	Version_change	1	07 Apr 2004 11:29:31	WBPerson1971	Event	Imported	Initial conversion from geneace
		Status	Live
	Gene_info	Gene_class	msp
		Phenotype	[C.elegansII] NMK. Encodes MSP (16kD); msp-45 cluster. [Ward et al. (1988); BA]
		GO_term	GO:0005198	IEA	Inferred_automatically
		Structured_description	Provisional_description	msp-50 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.	Paper_evidence	WBPaper00001023
						WBPaper00002143
						WBPaper00004591
						WBPaper00005670
					Curator_confirmed	WBPerson324
					Date_last_updated	31 Mar 2005 00:00:00
			Concise_description	msp-50 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
	Molecular_info	Corresponding_CDS	C34F11.4
		Corresponding_protein	WP:CE02806
		Corresponding_PCR_product (31)
		Corresponding_RNAi_reagent (39)
	Experimental_info	RNAi_result	Cenix:236-g6
			JA:C34F11.4
		WB_RNAi_result (75)
		Expr_pattern	Expr3417
	Reference	WBPaper00001023
		WBPaper00024312
	Method	Gene