C34G6.4 | SMap | S_parent | Sequence | C34G6
|
| Chromosome | I |
|
Identity (5)
|
|
Gene_info
| Gene_class | pgp
|
| | Allele | gk114
| Inferred_automatically | From strain object: VC134 |
| | Phenotype | [C.elegansII] NMK. Encodes P-glycoprotein, 61-65% identical to mammalian P-glycoproteins. Transcript slow in egg, higher subsequently. [Lincke et al. 1993; Nl] |
| | Strain | VC134
|
| |
GO_term (7)
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| |
Structured_description
| Provisional_description | pgp-2 encodes a member of the ABC transporter family with highest similarity to the vertebrate MDR (multidrug resistance) family, and is orthologous to human MDR1 (ABCB1; OMIM:171050, mutated in Crohn disease); PGP-2 is expressed at lower levels during the embryonic stages with higher expression later in development. |
Paper_evidence
| WBPaper00001647
|
| | | | | | WBPaper00001717
|
| | | | | Person_evidence | WBPerson48
|
| | | | | Curator_confirmed | WBPerson48
|
| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | Concise_description | pgp-2 encodes a member of the ABC transporter family with highest similarity to the vertebrate MDR (multidrug resistance) family, and is orthologous to human MDR1 (ABCB1; OMIM:171050, mutated in Crohn disease); PGP-2 is expressed at lower levels during the embryonic stages with higher expression later in development. |
|
Molecular_info
| Corresponding_CDS | C34G6.4
|
| | Corresponding_protein | WP:CE29212
|
| | KOG | KOG0055
|
| |
Corresponding_PCR_product
| smd_C34G6.4
|
| | | sjj_C34G6.4
|
| |
Corresponding_RNAi_reagent
| Cenix:78-e1
|
| | | sjj_C34G6.4
|
| | | yk354c5
|
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Experimental_info (3)
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Reference (9)
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| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene
|