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Gene: C34G6.4   

C34G6.4SMapS_parentSequenceC34G6
ChromosomeI
Identity (5)
Gene_info Gene_classpgp
Allelegk114 Inferred_automaticallyFrom strain object: VC134
Phenotype[C.elegansII] NMK. Encodes P-glycoprotein, 61-65% identical to mammalian P-glycoproteins. Transcript slow in egg, higher subsequently. [Lincke et al. 1993; Nl]
StrainVC134
GO_term (7)
Structured_description Provisional_descriptionpgp-2 encodes a member of the ABC transporter family with highest similarity to the vertebrate MDR (multidrug resistance) family, and is orthologous to human MDR1 (ABCB1; OMIM:171050, mutated in Crohn disease); PGP-2 is expressed at lower levels during the embryonic stages with higher expression later in development. Paper_evidence WBPaper00001647
WBPaper00001717
Person_evidenceWBPerson48
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Concise_descriptionpgp-2 encodes a member of the ABC transporter family with highest similarity to the vertebrate MDR (multidrug resistance) family, and is orthologous to human MDR1 (ABCB1; OMIM:171050, mutated in Crohn disease); PGP-2 is expressed at lower levels during the embryonic stages with higher expression later in development.
Molecular_info Corresponding_CDSC34G6.4
Corresponding_proteinWP:CE29212
KOGKOG0055
Corresponding_PCR_product smd_C34G6.4
sjj_C34G6.4
Corresponding_RNAi_reagent Cenix:78-e1
sjj_C34G6.4
yk354c5
Experimental_info (3)
Reference WBPaper00002619
WBPaper00002180
WBPaper00001717
WBPaper00001784
WBPaper00006437
WBPaper00014754
WBPaper00014953
WBPaper00015110
WBPaper00001647
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene