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Gene: C34G6.4   

C34G6.4SMapS_parentSequenceC34G6
ChromosomeI
Identity (5)
Gene_info Gene_classpgp
Allelegk114 Inferred_automaticallyFrom strain object: VC134
Phenotype[C.elegansII] NMK. Encodes P-glycoprotein, 61-65% identical to mammalian P-glycoproteins. Transcript slow in egg, higher subsequently. [Lincke et al. 1993; Nl]
StrainVC134
GO_term (7)
Structured_description Provisional_descriptionpgp-2 encodes a member of the ABC transporter family with highest similarity to the vertebrate MDR (multidrug resistance) family, and is orthologous to human MDR1 (ABCB1; OMIM:171050, mutated in Crohn disease); PGP-2 is expressed at lower levels during the embryonic stages with higher expression later in development. Paper_evidence WBPaper00001647
WBPaper00001717
Person_evidenceWBPerson48
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Concise_descriptionpgp-2 encodes a member of the ABC transporter family with highest similarity to the vertebrate MDR (multidrug resistance) family, and is orthologous to human MDR1 (ABCB1; OMIM:171050, mutated in Crohn disease); PGP-2 is expressed at lower levels during the embryonic stages with higher expression later in development.
Molecular_info Corresponding_CDSC34G6.4
Corresponding_proteinWP:CE29212
KOGKOG0055
Corresponding_PCR_product smd_C34G6.4
sjj_C34G6.4
Corresponding_RNAi_reagent (3)
Experimental_info (3)
Reference (9)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene