Gene: C34G6.4
C34G6.4 | SMap | S_parent | Sequence | C34G6 | ||
---|---|---|---|---|---|---|
Chromosome | I | |||||
Identity (5) | ||||||
Gene_info | Gene_class | pgp | ||||
Allele | gk114 | Inferred_automatically | From strain object: VC134 | |||
Phenotype | [C.elegansII] NMK. Encodes P-glycoprotein, 61-65% identical to mammalian P-glycoproteins. Transcript slow in egg, higher subsequently. [Lincke et al. 1993; Nl] | |||||
Strain | VC134 | |||||
GO_term (7) | ||||||
Structured_description | Provisional_description | pgp-2 encodes a member of the ABC transporter family with highest similarity to the vertebrate MDR (multidrug resistance) family, and is orthologous to human MDR1 (ABCB1; OMIM:171050, mutated in Crohn disease); PGP-2 is expressed at lower levels during the embryonic stages with higher expression later in development. | Paper_evidence | WBPaper00001647 | ||
WBPaper00001717 | ||||||
Person_evidence | WBPerson48 | |||||
Curator_confirmed | WBPerson48 | |||||
Date_last_updated | 17 Jun 2004 00:00:00 | |||||
Concise_description | pgp-2 encodes a member of the ABC transporter family with highest similarity to the vertebrate MDR (multidrug resistance) family, and is orthologous to human MDR1 (ABCB1; OMIM:171050, mutated in Crohn disease); PGP-2 is expressed at lower levels during the embryonic stages with higher expression later in development. | |||||
Molecular_info (5) | ||||||
Experimental_info | RNAi_result (6) | |||||
WB_RNAi_result | JA:C34G6.4 | |||||
SA:yk354c5 | ||||||
[cgc5655]:C34G6.4 | ||||||
[cgc5655]:daf-2:C34G6.4 | ||||||
[cgc5655]:tph-1:C34G6.4 | ||||||
[cgc5655]:tub-1:C34G6.4 | ||||||
Cenix:78-e1 | ||||||
Expr_pattern (2) | ||||||
Reference (9) | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |