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Gene: C43E11.10   

C43E11.10SMapS_parentSequenceC43E11
ChromosomeI
Identity (5)
Gene_info Gene_classcdc
GO_term GO:0000166 IEA Inferred_automatically
GO:0017111 IEA Inferred_automatically
Contained_in_operonCEOP1172
Structured_description Provisional_description cdc-6 encodes a homolog of an origin complex component (CDC6) which in yeast controls the start of DNA replication, and also has a distant paralog (Y39A1A.12) within the C. elegans genome; CDC-6 is superficially dispensable for embryonic viability, perhaps because of redundancy with Y39A1A.12.Paper_evidenceWBPaper00013079
Person_evidenceWBPerson567
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
At the end of mitosis in yeast, the MCM complex is loaded on to chromatin with the aid of ORC, Cdc6/18 and Cdt1, and chromatin becomes licensed for replication; this licensing is essential to ensure that the genome is replicated exactly once per cell cycle.
Concise_descriptioncdc-6 encodes a homolog of an origin complex component (CDC6) which in yeast controls the start of DNA replication, and also has a distant paralog (Y39A1A.12) within the C. elegans genome; CDC-6 is superficially dispensable for embryonic viability, perhaps because of redundancy with Y39A1A.12.
Molecular_info (5)
Experimental_info RNAi_result (5)
WB_RNAi_result JA:C43E11.10
MV_SV:mv_C43E11.10
Cenix:74-a3
Reference (2)
MethodGene