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Gene: C43E11.7   

C43E11.7SMapS_parentSequenceC43E11
ChromosomeI
Identity Version1
Name CGC_namendx-7 Person_evidenceWBPerson3090
Sequence_nameC43E11.7
Molecular_name C43E11.7
WP:CE30504
CE30504
Other_name NM_058935 Inferred_automatically
Date_last_updated15 Apr 2005 00:00:00 WS142
Public_namendx-7
Synonym (5)
WBGeneIDWBGene00003584
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:32WBPerson1971 EventImportedInitial conversion from geneace
StatusLive
Gene_info Gene_classndx
Allele uCE1-820
uCE1-821
Contained_in_operonCEOP1160
Structured_description Provisional_description (5)
Concise_descriptionndx-7 encodes a NUDIX hydrolase; by sequence comparison, NDX-7 is predicted to function as a pyrophosphatase, and is most closely related to the mouse RP2 protein that has unknown substrate specificity but is regulated transcriptionally by the presence of androgens; in C. elegans, loss of ndx-7 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways.
Molecular_info (5)
Experimental_info RNAi_result Cenix:159-e1
JA:C43E11.7
WB_RNAi_result JA:C43E11.7
MV_SV:mv_C43E11.7
Cenix:159-e1
ReferenceWBPaper00005401
MethodGene