Gene: CD4.2
CD4.2 | Evidence | Paper_evidence | WBPaper00005857 | |
---|---|---|---|---|
SMap | S_parent | Sequence | CD4 | |
Chromosome | V | |||
Identity (5) | ||||
Gene_info | Gene_class | crn | ||
Contained_in_operon | CEOP5076 | |||
Structured_description | Provisional_description (9) | |||
Concise_description | crn-2 encodes a cell death-related nuclease, homologous to the magnesium-dependant TatD nuclease of E. coli; CRN-2 is required for normal levels of DNA degradation during apoptosis; crn-2(RNAi) 1.5-fold stage embryos display TUNEL labelling of nuclei that is five-fold higher than that seen in untreated N2 animals; CRN-2 promotes both DNA degradation and cell corpse engulfment, in a partially redundant pathway that includes CRN-3 but is parallel to CPS-6; CRN-2 is predicted to be mitochondrial. | |||
Molecular_info | Corresponding_CDS | CD4.2 | ||
Corresponding_protein | WP:CE16950 | |||
KOG | KOG3020 | |||
Corresponding_PCR_product | smd_CD4.2 | |||
sjj_CD4.2 | ||||
Corresponding_RNAi_reagent | Cenix:174-f2 | |||
sjj_CD4.2 | ||||
mv_CD4.2 | ||||
Other_sequence | AY303576 | |||
Experimental_info | RNAi_result | Cenix:174-f2 | ||
JA:CD4.2 | ||||
WB_RNAi_result | JA:CD4.2 | |||
MV_SV:mv_CD4.2 | ||||
Cenix:174-f2 | ||||
Expr_pattern | Expr5044 | |||
Interaction | WBInteraction0002090 | |||
WBInteraction0002091 | ||||
Reference | WBPaper00005857 | |||
WBPaper00006283 | ||||
WBPaper00019408 | ||||
Method | Gene |