RNAiDB Tree View

Gene: CD4.6

CD4.6	Evidence	CGC_data_submission
	SMap	S_parent	Sequence	CD4
	Chromosome	V
	Identity (5)
	Gene_info	Gene_class	pas
		Allele	tm1942
		GO_term	GO:0004298	IEA	Inferred_automatically
			GO:0006511	IEA	Inferred_automatically
			GO:0005839	IEA	Inferred_automatically
			GO:0004175	IEA	Inferred_automatically
		Structured_description	Provisional_description	pas-6 encodes a type 1 alpha subunit of the 26S proteasome's 20S protease core particle (CP); PAS-6 is required for embryonic, larval, and germline development and by homology, is predicted to comprise the outer rings of the proteasome and to play a role in selective degradation of ubiquitinated proteins during development; in vitro, PAS-6 interacts with BRP-1, a glutamine/asparagine (Q/N)-rich domain-containing protein conserved amongst nematodes, and with other members of the proteasome.	Paper_evidence (2)
					Person_evidence	WBPerson1843
					Curator_confirmed	WBPerson1843
					Date_last_updated	17 Jun 2004 00:00:00
			Concise_description	pas-6 encodes a type 1 alpha subunit of the 26S proteasome's 20S protease core particle (CP); PAS-6 is required for embryonic, larval, and germline development and by homology, is predicted to comprise the outer rings of the proteasome and to play a role in selective degradation of ubiquitinated proteins during development; in vitro, PAS-6 interacts with BRP-1, a glutamine/asparagine (Q/N)-rich domain-containing protein conserved amongst nematodes, and with other members of the proteasome.
	Molecular_info (5)
	Experimental_info	RNAi_result	Cenix:23-f5
			JA:CD4.6
			Simmer:CD4.6
		WB_RNAi_result	JA:CD4.6
			Simmer:CD4.6
			Cenix:23-f5
	Reference	WBPaper00026640
	Remark	Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.	CGC_data_submission
	Method	Gene