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Gene: DH11.3   

DH11.3SMapS_parentSequenceDH11
ChromosomeII
Identity (5)
Gene_info Gene_classpgp
Alleletm333
GO_term (7)
Structured_description Provisional_descriptionpgp-11 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; by homology, PGP-11 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins; however, as loss of pgp-11 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-11 in C. elegans development and/or behavior is not yet known.Paper_evidenceWBPaper00005654
Person_evidenceWBPerson1843
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Concise_descriptionpgp-11 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; by homology, PGP-11 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins; however, as loss of pgp-11 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-11 in C. elegans development and/or behavior is not yet known.
Molecular_info (6)
Experimental_info RNAi_result Cenix:246-e5
JA:DH11.3
WB_RNAi_result JA:DH11.3
Cenix:246-e5
Expr_pattern Expr3338
Expr5200
Remark Sequence connection from [Sheps JA, Baillie DL] [040902 ck1]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene