RNAiDB Tree View

Gene: DH11.3

DH11.3	SMap	S_parent	Sequence	DH11
	Chromosome	II
	Identity (5)
	Gene_info	Gene_class	pgp
		Allele	tm333
		GO_term (7)
		Structured_description	Provisional_description	pgp-11 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; by homology, PGP-11 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins; however, as loss of pgp-11 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-11 in C. elegans development and/or behavior is not yet known.	Paper_evidence	WBPaper00005654
					Person_evidence	WBPerson1843
					Curator_confirmed	WBPerson1843
					Date_last_updated	17 Jun 2004 00:00:00
			Concise_description	pgp-11 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; by homology, PGP-11 is predicted to function as an ATP-dependent efflux pump that protects C. elegans by exporting exogenous toxins; however, as loss of pgp-11 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of PGP-11 in C. elegans development and/or behavior is not yet known.
	Molecular_info (6)
	Experimental_info	RNAi_result	Cenix:246-e5
			JA:DH11.3
		WB_RNAi_result (2)
		Expr_pattern	Expr3338
			Expr5200
	Remark	Sequence connection from [Sheps JA, Baillie DL] [040902 ck1]
		Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.	CGC_data_submission
	Method	Gene