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Gene: F01G4.2 
| F01G4.2 | SMap | S_parent | Sequence | F01G4 | ||
|---|---|---|---|---|---|---|
| Chromosome | IV | |||||
| Identity (5) | ||||||
| Gene_info | Gene_class | ard | ||||
| GO_term | GO:0016491 | IEA | Inferred_automatically | |||
| GO:0008152 | IEA | Inferred_automatically | ||||
| GO:0004197 | IEA | Inferred_automatically | ||||
| GO:0006508 | IEA | Inferred_automatically | ||||
| Contained_in_operon | CEOP4412 | |||||
| Structured_description | Provisional_description | ard-1 encodes a homolog of mammalian 3-hydroxyacyl-CoA dehydrogenase (HADH II)/amyloid-beta binding alcohol dehydrogenase (ABAD) that is predicted to be mitochondrial. | Paper_evidence | WBPaper00004424 | ||
| WBPaper00012828 | ||||||
| WBPaper00013599 | ||||||
| WBPaper00013615 | ||||||
| Person_evidence | WBPerson567 | |||||
| Curator_confirmed | WBPerson567 | |||||
| Date_last_updated | 17 Jun 2004 00:00:00 | |||||
| This gene encodes a protein predicted by Eisenberg and coworkers, with 68% accuracy, to be mitochondrial. | ||||||
| Proteins localized to a given organelle by experiments tend to share a characteristic phylogenetic distribution of their homologs, called a phylogenetic profile. | ||||||
| For instance, mitochondrial proteins can be identified effectively by their phylogenetic profiles. | ||||||
| By applying phylogenetic profile analysis to the C. elegans genome, Eisenberg and coworkers inferred that this gene, along with 2-4% of all the nuclear genes in C. elegans, encodes a mitochondrial protein. | ||||||
| The large fraction of organism-specific and eukaryote-derived genes suggests that C. elegans mitochondria perform specialized roles absent from prokaryotic mitochondrial ancestors. | ||||||
| Concise_description | ard-1 encodes a homolog of mammalian 3-hydroxyacyl-CoA dehydrogenase (HADH II)/amyloid-beta binding alcohol dehydrogenase (ABAD) that is predicted to be mitochondrial. | |||||
| Molecular_info (5) | ||||||
| Experimental_info | RNAi_result | JA:F01G4.2 | ||||
| Simmer:F01G4.2:Repeat_a | ||||||
| Simmer:F01G4.2:Screen | ||||||
| Cenix:180-g1 | ||||||
| WB_RNAi_result (5) | ||||||
| Reference | WBPaper00026640 | |||||
| Remark | The name sad was previously used for this Short-chain Alcohol Dehydrogenase ERAB family by Carl Johnson. | |||||
| Method | Gene |
