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Gene: F11C1.6   

F11C1.6Evidence Paper_evidence WBPaper00003416
WBPaper00004124
WBPaper00004329
SMapS_parentSequenceF11C1
ChromosomeX
Identity (5)
Gene_info Gene_classnhr
Allele jm2389 Inferred_automaticallyFrom strain object: HL2000
ok645 Inferred_automaticallyFrom strain object: VC469
ku217 Paper_evidenceWBPaper00024419
Phenotype[M Asahina] jm2389 is mutagenized using TMP/UV and detected a deletion by PCR. This removes the coding region from Gly40 in the P-box of the first zinc finger motif to Ser377 in the middle of the conserved region II within the LBD (ref. Asahina M et al. 2000 The conserved nuclear receptor Ftz-F1 is required for embryogenesis, moulting and reproduction in Caenorhabditis elegans. Genes to Cells 5: 711). Phenotype is homozygous embryonic lethal at 1.5-fold to 2-fold stage. Balanced with +/szT1[lon-2(e678)] I; nDf19/szT1 X (strain MT1401)
Strain HL2000
VC469
GO_term (6)
Structured_description Provisional_descriptionnhr-25 encodes a nuclear hormone receptor orthologous to Drosophila Ftz-F1; NHR-25 is required for embryogenesis, molting, vulval and gonadal development, and hypodermal expression of acn-1; nhr-25 is expressed in gonads and loaded into embryos as a maternal transcript; nhr-25 is zygotically expressed in progeny of the E cell, and then in hypodermis and gut; the role of NHR-25 in molting may be evolutionarily conserved between nematodes and arthopods. Paper_evidence WBPaper00004329
WBPaper00006295
WBPaper00013324
Person_evidenceWBPerson567
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Concise_descriptionnhr-25 encodes a nuclear hormone receptor orthologous to Drosophila Ftz-F1; NHR-25 is required for embryogenesis, molting, vulval and gonadal development, and hypodermal expression of acn-1; nhr-25 is expressed in gonads and loaded into embryos as a maternal transcript; nhr-25 is zygotically expressed in progeny of the E cell, and then in hypodermis and gut; the role of NHR-25 in molting may be evolutionarily conserved between nematodes and arthopods.
Molecular_info Corresponding_CDS F11C1.6a
F11C1.6b
Corresponding_protein WP:CE03191
WP:CE35856
Corresponding_PCR_product smd_F11C1.6
sjj_F11C1.6
Corresponding_RNAi_reagent Cenix:53-b7
sjj_F11C1.6
probe_1:F11C1
Other_sequence AF179214
AF179215
AF179216
Experimental_info (3)
Reference (27)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene