F11C1.6 | Evidence |
Paper_evidence
| WBPaper00003416
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| | | WBPaper00004124
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| | | WBPaper00004329
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| SMap | S_parent | Sequence | F11C1
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| Chromosome | X |
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Identity (5)
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Gene_info
| Gene_class | nhr
|
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Allele
| jm2389
| Inferred_automatically | From strain object: HL2000 |
| | | ok645
| Inferred_automatically | From strain object: VC469 |
| | | ku217
| Paper_evidence | WBPaper00024419
|
| | Phenotype | [M Asahina] jm2389 is mutagenized using TMP/UV and detected a deletion by PCR. This removes the coding region from Gly40 in the P-box of the first zinc finger motif to Ser377 in the middle of the conserved region II within the LBD (ref. Asahina M et al. 2000 The conserved nuclear receptor Ftz-F1 is required for embryogenesis, moulting and reproduction in Caenorhabditis elegans. Genes to Cells 5: 711). Phenotype is homozygous embryonic lethal at 1.5-fold to 2-fold stage. Balanced with +/szT1[lon-2(e678)] I; nDf19/szT1 X (strain MT1401) |
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Strain (2)
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GO_term (6)
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Structured_description
| Provisional_description | nhr-25 encodes a nuclear hormone receptor orthologous to Drosophila Ftz-F1; NHR-25 is required for embryogenesis, molting, vulval and gonadal development, and hypodermal expression of acn-1; nhr-25 is expressed in gonads and loaded into embryos as a maternal transcript; nhr-25 is zygotically expressed in progeny of the E cell, and then in hypodermis and gut; the role of NHR-25 in molting may be evolutionarily conserved between nematodes and arthopods. |
Paper_evidence
| WBPaper00004329
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| | | | | | WBPaper00006295
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| | | | | | WBPaper00013324
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| | | | | Person_evidence | WBPerson567
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| | | | | Curator_confirmed | WBPerson567
|
| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | Concise_description | nhr-25 encodes a nuclear hormone receptor orthologous to Drosophila Ftz-F1; NHR-25 is required for embryogenesis, molting, vulval and gonadal development, and hypodermal expression of acn-1; nhr-25 is expressed in gonads and loaded into embryos as a maternal transcript; nhr-25 is zygotically expressed in progeny of the E cell, and then in hypodermis and gut; the role of NHR-25 in molting may be evolutionarily conserved between nematodes and arthopods. |
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Molecular_info (5)
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Experimental_info
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RNAi_result
| JA:F11C1.6
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| | | Simmer:F11C1.6
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| | | [cgc5655]:F11C1.6
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| | | [cgc5655]:daf-2:F11C1.6
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| | | [cgc5655]:tph-1:F11C1.6
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| | | [cgc5655]:tub-1:F11C1.6
|
| | | Cenix:53-b7
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WB_RNAi_result (14)
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Expr_pattern (7)
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Reference (27)
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| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene
|