Gene: F11C3.2
F11C3.2 | Evidence | CGC_data_submission | ||||
---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F11C3 | |||
Chromosome | I | |||||
Identity (5) | ||||||
Gene_info | Gene_class | unc | ||||
Allele | e2520 | Inferred_automatically | From strain object: CB4870 | |||
n2916 | Paper_evidence | WBPaper00006427 | ||||
Inferred_automatically | From strain object: CB51 | |||||
ox79 | Paper_evidence | WBPaper00006427 | ||||
Phenotype | [C.elegansII] e2520 : medium coiler at all stages. Moves forward well when stimulated, tends to coil up when moving backwards or at rest. Coiling usually ventral, occasionally dorsal. ES2 ME1/ME2. NA1. [CB] | |||||
Strain | CB51 | |||||
CB4870 | ||||||
GO_term | GO:0006817 | IEA | Inferred_automatically | |||
GO:0005737 | IEA | Inferred_automatically | ||||
Structured_description | Provisional_description | unc-122 encodes a predicted type II transmembrane protein with extracellular collagen-like domains and a highly conserved olfactomedin (OLF) domain that is found in a family of secreted proteins involved in formation and function of nervous systems; UNC-122 is required for proper locomotion and for normal morphology of the DVB motorneuron, and may regulate neuromuscular function by acting in an aminergic/peptidergic pathway parallel to cholinergic neurotransmission; although mosaic analysis indicates that UNC-122 activity is required in muscle cells, the precise expression and localization patterns of UNC-122 are not yet known. | Paper_evidence | WBPaper00002665 | ||
WBPaper00012807 | ||||||
WBPaper00015718 | ||||||
WBPaper00017559 | ||||||
Person_evidence | WBPerson1843 | |||||
Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 17 Jun 2004 00:00:00 | |||||
Concise_description | unc-122 encodes a predicted type II transmembrane protein with extracellular collagen-like domains and a highly conserved olfactomedin (OLF) domain that is found in a family of secreted proteins involved in formation and function of nervous systems; UNC-122 is required for proper locomotion and for normal morphology of the DVB motorneuron, and may regulate neuromuscular function by acting in an aminergic/peptidergic pathway parallel to cholinergic neurotransmission; although mosaic analysis indicates that UNC-122 activity is required in muscle cells, the precise expression and localization patterns of UNC-122 are not yet known. | |||||
Molecular_info (6) | ||||||
Experimental_info | RNAi_result | Cenix:147-a1 | ||||
WB_RNAi_result | MV_SV:mv_F11C3.2 | |||||
Cenix:147-a1 | ||||||
Expr_pattern | Expr2859 | |||||
Expr2860 | ||||||
Expr5327 | ||||||
Interaction | WBInteraction0002346 | |||||
WBInteraction0002347 | ||||||
WBInteraction0002348 | ||||||
Reference | WBPaper00006427 | |||||
WBPaper00015718 | ||||||
WBPaper00016962 | ||||||
WBPaper00018118 | ||||||
WBPaper00022023 | ||||||
WBPaper00024232 | ||||||
Remark | [Hodgkin JA] extracted from complex strain CB3337, isolated by Hedgecock EM | |||||
Sequence connection from [Loria P, Hobert O] | ||||||
Method | Gene |