Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 

Gene: F11H8.3   

F11H8.3SMapS_parentSequenceF11H8
ChromosomeIII
Identity (5)
Gene_info Gene_classcol
Phenotype Transcript present in dauer larvae and adults.
[C.elegansII] NMK. Transcript present in dauer larvae and adults;not detected in egg or L4. Encodes collagen,col-8 family includes col-19,35,39. [Cox and Hirsh 1985]
GO_term GO:0042302 IEA Inferred_automatically
GO:0006817 IEA Inferred_automatically
GO:0005737 IEA Inferred_automatically
Structured_description Provisional_description col-8 encodes a collagen, individually dispensable for viability and gross morphology, which is specifically expressed in dauers and adults but not in eggs or L4 larvae, like col-7, col-18, and col-19; the amino- and carboxyl-terminal cysteine-rich regions of COL-8 are most closely related to those of COL-19, COL-35, and COL-39. Paper_evidence WBPaper00000748
WBPaper00001918
Person_evidenceWBPerson567
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Collagen genes with a dauer- and adult-specific expression pattern may be used to generate characteristics specific to cuticles at these stages.
The morphology of the C. elegans L1 cuticle is typical of that seen in cuticles of many nematode species, and therefore may represent a 'primitive' cuticle morphology; more elaborate cuticles at later stages may be evolutionary specializations arising from the diversification of collagens expressed in post-L1 stages, such as col-8.
Concise_descriptioncol-8 encodes a collagen, individually dispensable for viability and gross morphology, which is specifically expressed in dauers and adults but not in eggs or L4 larvae, like col-7, col-18, and col-19; the amino- and carboxyl-terminal cysteine-rich regions of COL-8 are most closely related to those of COL-19, COL-35, and COL-39.
Molecular_info (6)
Experimental_info RNAi_result Cenix:304-h11
JA:F11H8.3
TH:304H11
WB_RNAi_result (8)
Expr_patternExpr765
Reference (19)
MethodGene