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Gene: F11H8.4 
| F11H8.4 | SMap | S_parent | Sequence | F11H8 | ||
|---|---|---|---|---|---|---|
| Chromosome | III | |||||
| Identity (5) | ||||||
| Gene_info | Gene_class | cyk | ||||
| Allele (5) | ||||||
| Phenotype | [Bowerman B] cytokinesis defective. Recessive, maternal-effect, embryonic lethal | |||||
| [Stewart HI] homozygotes develop into sterile adults | ||||||
| [Schnabel H] other name: let-794 NA4 | ||||||
| Strain | BC4863 | |||||
| EU396 | ||||||
| GE2238 | ||||||
| GE2722 | ||||||
| GO_term | GO:0003779 | IEA | Inferred_automatically | |||
| GO:0016043 | IEA | Inferred_automatically | ||||
| Structured_description | Provisional_description | The cyk-1 gene encodes a homolog of Drosophila diaphanous and human DIAPH1. | Paper_evidence | WBPaper00004103 | ||
| Person_evidence | WBPerson567 | |||||
| Curator_confirmed | WBPerson567 | |||||
| Date_last_updated | 17 Jun 2004 00:00:00 | |||||
| Mutation of human DIAPH1 leads to non-syndromic deafness DFNA1 (OMIM:124900). | ||||||
| Concise_description | The cyk-1 gene encodes a homolog of Drosophila diaphanous and human DIAPH1. | |||||
| Molecular_info (5) | ||||||
| Experimental_info | RNAi_result | Cenix:304-a12 | ||||
| JA:F11H8.4 | ||||||
| Simmer:F11H8.4 | ||||||
| TH:304a12 | ||||||
| WB_RNAi_result (5) | ||||||
| Expr_pattern | Expr1411 | |||||
| Interaction | WBInteraction0001310 | |||||
| WBInteraction0001744 | ||||||
| WBInteraction0002004 | ||||||
| WBInteraction0002666 | ||||||
| Reference (25) | ||||||
| Remark | F11H8.4 is a genefinder predicted gene with homology to diaphanous in Drosophila and cdc-12 in S. pombe, both of which are required for cytokinesis | |||||
| The mutation s2833 was previously assigned to let-794. | ||||||
| Method | Gene |
