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Gene: F13B10.2   

F13B10.2SMapS_parentSequenceSUPERLINK_CB_IIIL
ChromosomeIII
Identity (5)
Gene_info Gene_classrpl
PhenotypeOrthologous to yeast (S.cerevisiae) ribosomal protein rpl3 using blastP
GO_term GO:0003735 IEA Inferred_automatically
GO:0006412 IEA Inferred_automatically
GO:0005622 IEA Inferred_automatically
GO:0005840 IEA Inferred_automatically
Structured_description Provisional_descriptionrpl-3 encodes a large ribosomal subunit L3 protein required in mass RNAi assays for embryonic and larval viability, fertility, and general health; the rpl-3 transcription unit has a nonsense transcript that is up-regulated in vivo by smg[-] mutations, indicating that rpl-3 is a natural substrate for SMG-mediated nonsense suppresssion; several other natural mRNA substrates of SMG suppression (e.g., rpl-7, rpl-10, rpl-12) have protein products that are involved in translation. Paper_evidence WBPaper00004313
WBPaper00004403
WBPaper00004651
WBPaper00005654
Person_evidenceWBPerson567
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Concise_descriptionrpl-3 encodes a large ribosomal subunit L3 protein required in mass RNAi assays for embryonic and larval viability, fertility, and general health; the rpl-3 transcription unit has a nonsense transcript that is up-regulated in vivo by smg[-] mutations, indicating that rpl-3 is a natural substrate for SMG-mediated nonsense suppresssion; several other natural mRNA substrates of SMG suppression (e.g., rpl-7, rpl-10, rpl-12) have protein products that are involved in translation.
Molecular_info (5)
Experimental_info RNAi_result Cenix:320-c6
JA:F13B10.2
Simmer:F13B10.2
TH:320c6
WB_RNAi_result (5)
Y2H_target (6)
Reference WBPaper00004313
WBPaper00006081
WBPaper00026063
Remarkdata taken from http://www.sanger.ac.uk/Projects/C_elegans/ANNOTATION/ribosomal_protein/
MethodGene