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Gene: F15H10.2   

F15H10.2SMapS_parentSequenceF15H10
ChromosomeV
Identity (5)
Gene_info Gene_classcol
Phenotype[C.elegansII] NMK. Transcript present at all stages. Encodes collagen, col-6 family.Linked to col-12. [Cox and Hirsh 1985]
GO_term GO:0042302 IEA Inferred_automatically
GO:0006817 IEA Inferred_automatically
GO:0005737 IEA Inferred_automatically
Structured_description Provisional_description col-13 encodes a collagen which is expressed in all stages of development, like sqt-3 (col-1), col-3, col-10, col-11, col-12, and col-14; collagen genes with this expression profile may be specifically required to construct the L1 cuticle (and, perhaps, less specifically required for cuticles at other stages); the amino- and carboxyl-terminal cysteine-rich regions of COL-13 are most closely related to those of COL-6, COL-12, COL-14, COL-36, and COL-40. Paper_evidence WBPaper00000748
WBPaper00001918
Person_evidenceWBPerson567
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
The morphology of the C. elegans L1 cuticle is typical of that seen in cuticles of many nematode species, and therefore may represent a 'primitive' cuticle morphology, which genes like col-13 may promote; more elaborate cuticles at later stages may be evolutionary specializations arising from the diversification of collagens expressed in post-L1 stages.
Concise_descriptioncol-13 encodes a collagen which is expressed in all stages of development, like sqt-3 (col-1), col-3, col-10, col-11, col-12, and col-14; collagen genes with this expression profile may be specifically required to construct the L1 cuticle (and, perhaps, less specifically required for cuticles at other stages); the amino- and carboxyl-terminal cysteine-rich regions of COL-13 are most closely related to those of COL-6, COL-12, COL-14, COL-36, and COL-40.
Molecular_info (6)
Experimental_info RNAi_resultCenix:243-g11
WB_RNAi_result (5)
Expr_pattern Expr757
Expr768
Expr2432
Reference (13)
MethodGene