F15H10.2 | SMap | S_parent | Sequence | F15H10
|
| Chromosome | V |
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Identity (5)
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Gene_info
| Gene_class | col
|
| | Phenotype | [C.elegansII] NMK. Transcript present at all stages. Encodes collagen, col-6 family.Linked to col-12. [Cox and Hirsh 1985] |
| |
GO_term
| GO:0042302
| IEA
| Inferred_automatically |
| | | GO:0006817
| IEA
| Inferred_automatically |
| | | GO:0005737
| IEA
| Inferred_automatically |
| |
Structured_description
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Provisional_description
| col-13 encodes a collagen which is expressed in all stages of development, like sqt-3 (col-1), col-3, col-10, col-11, col-12, and col-14; collagen genes with this expression profile may be specifically required to construct the L1 cuticle (and, perhaps, less specifically required for cuticles at other stages); the amino- and carboxyl-terminal cysteine-rich regions of COL-13 are most closely related to those of COL-6, COL-12, COL-14, COL-36, and COL-40. |
Paper_evidence
| WBPaper00000748
|
| | | | | | WBPaper00001918
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| | | | | Person_evidence | WBPerson567
|
| | | | | Curator_confirmed | WBPerson567
|
| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | | The morphology of the C. elegans L1 cuticle is typical of that seen in cuticles of many nematode species, and therefore may represent a 'primitive' cuticle morphology, which genes like col-13 may promote; more elaborate cuticles at later stages may be evolutionary specializations arising from the diversification of collagens expressed in post-L1 stages. |
| | | Concise_description | col-13 encodes a collagen which is expressed in all stages of development, like sqt-3 (col-1), col-3, col-10, col-11, col-12, and col-14; collagen genes with this expression profile may be specifically required to construct the L1 cuticle (and, perhaps, less specifically required for cuticles at other stages); the amino- and carboxyl-terminal cysteine-rich regions of COL-13 are most closely related to those of COL-6, COL-12, COL-14, COL-36, and COL-40. |
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Molecular_info (6)
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Experimental_info
| RNAi_result | Cenix:243-g11
|
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WB_RNAi_result (5)
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Expr_pattern
| Expr757
|
| | | Expr768
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| | | Expr2432
|
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Reference (13)
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| Method | Gene
|