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Gene: F26D10.3   

F26D10.3SMapS_parentSequenceSUPERLINK_CB_IV
ChromosomeIV
Identity (5)
Gene_info Gene_classhsp
Phenotype[C.elegansII] NMK. Encodes protein related to generic hsp70. Quite strong expression normally, only weak heat shock induction. [Heschl and Baillie 1990; BC]
GO_term GO:0009408 (2)
GO:0008340 IMP Paper_evidenceWBPaper00013354
Curator_confirmedWBPerson324
GO:0005524 IEA Inferred_automatically
Structured_description Provisional_description hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regulation of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity. Paper_evidence WBPaper00001048
WBPaper00001320
WBPaper00013354
Curator_confirmedWBPerson324
Date_last_updated17 Jun 2004 00:00:00
hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regualtion of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity. Paper_evidence WBPaper00001048
WBPaper00001320
WBPaper00013354
Person_evidenceWBPerson324
Concise_description hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regulation of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity.
hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regualtion of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity.
Molecular_info Corresponding_CDSF26D10.3
Corresponding_proteinWP:CE09682
KOGKOG0101
Corresponding_PCR_product smd_F26D10.3
smd_K09C4.3
smd_T28F3.2
sjj_T28F3.2
sjj_C15H9.6
sjj_K09C4.3
sjj_F26D10.3
Corresponding_RNAi_reagent (9)
Experimental_info RNAi_result Cenix:122-e2
Simmer:F26D10.3
Simmer:T28F3.2
WB_RNAi_result (7)
Expr_pattern Expr563
Expr5002
Y2H_target Y2H008858
Y2H008861
Y2H008862
Y2H008864
Reference WBPaper00017845
WBPaper00002044
WBPaper00001136
WBPaper00001159
WBPaper00001320
WBPaper00006377
WBPaper00013797
WBPaper00014145
WBPaper00014364
WBPaper00015338
WBPaper00022866
WBPaper00015440
WBPaper00006047
WBPaper00025088
WBPaper00025163
WBPaper00005475
WBPaper00026640
MethodGene