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Gene: F26D10.3   

F26D10.3SMapS_parentSequenceSUPERLINK_CB_IV
ChromosomeIV
Identity Version1
Name (7)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:26WBPerson1971 EventImportedInitial conversion from geneace
StatusLive
Gene_info Gene_classhsp
Phenotype[C.elegansII] NMK. Encodes protein related to generic hsp70. Quite strong expression normally, only weak heat shock induction. [Heschl and Baillie 1990; BC]
GO_term GO:0009408 IDA (2)
ISS Paper_evidenceWBPaper00001048
Curator_confirmedWBPerson324
GO:0008340 IMP Paper_evidenceWBPaper00013354
Curator_confirmedWBPerson324
GO:0005524 IEA Inferred_automatically
Structured_description Provisional_description hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regulation of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity. Paper_evidence (3)
Curator_confirmedWBPerson324
Date_last_updated17 Jun 2004 00:00:00
hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regualtion of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity. Paper_evidence (3)
Person_evidenceWBPerson324
Concise_description hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regulation of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity.
hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regualtion of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity.
Molecular_info (5)
Experimental_info RNAi_result Cenix:122-e2
Simmer:F26D10.3
Simmer:T28F3.2
WB_RNAi_result (7)
Expr_pattern Expr563
Expr5002
Y2H_target (4)
Reference (17)
MethodGene