Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 

Gene: F26G1.7   

F26G1.7SMapS_parentSequenceF26G1
ChromosomeII
Identity (5)
Gene_info Gene_classmsp
Phenotype Cluster of three genes including msp-3 (transcribed).
[C.elegansII] NMK. Encodes major sperm protein MSP (16kD) In cluster of three genes including msp-3. [Ward et al. (1988); BA]
GO_termGO:0005198 IEA Inferred_automatically
Structured_description Provisional_descriptionmsp-3 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-3 is similar in nucleotide sequence to the msp genes from the nematode Onchocerca volvulus; the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP proteins assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. Paper_evidence (5)
Curator_confirmedWBPerson324
Date_last_updated26 Apr 2005 00:00:00
Concise_descriptionmsp-3 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-3 is similar in nucleotide sequence to the msp genes from the nematode Onchocerca volvulus; the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP proteins assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
Molecular_info Corresponding_CDSF26G1.7
Corresponding_proteinWP:CE02699
Corresponding_PCR_product (50)
Corresponding_RNAi_reagent (54)
Experimental_info RNAi_result Cenix:246-b8
JA:F26G1.7
WB_RNAi_result (69)
Expr_patternExpr3417
Reference WBPaper00001023
WBPaper00001175
WBPaper00001207
WBPaper00024312
WBPaper00025088
MethodGene