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Gene: F26G1.7   

F26G1.7SMapS_parentSequenceF26G1
ChromosomeII
Identity (5)
Gene_info Gene_classmsp
Phenotype Cluster of three genes including msp-3 (transcribed).
[C.elegansII] NMK. Encodes major sperm protein MSP (16kD) In cluster of three genes including msp-3. [Ward et al. (1988); BA]
GO_termGO:0005198 IEA Inferred_automatically
Structured_description Provisional_descriptionmsp-3 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-3 is similar in nucleotide sequence to the msp genes from the nematode Onchocerca volvulus; the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP proteins assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. Paper_evidence (5)
Curator_confirmedWBPerson324
Date_last_updated26 Apr 2005 00:00:00
Concise_descriptionmsp-3 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-3 is similar in nucleotide sequence to the msp genes from the nematode Onchocerca volvulus; the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP proteins assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
Molecular_info Corresponding_CDSF26G1.7
Corresponding_proteinWP:CE02699
Corresponding_PCR_product (50)
Corresponding_RNAi_reagent (54)
Experimental_info RNAi_result Cenix:246-b8
JA:F26G1.7
WB_RNAi_result JA:C04G2.4
JA:C09B9.6
JA:C34F11.4
JA:C34F11.6
JA:F09C12.7
JA:F26G1.7
JA:F32B6.6
JA:F36H12.7
JA:F58A6.8
JA:K05F1.7
JA:K07F5.1
JA:K07F5.2
JA:K07F5.3
JA:K08F4.8
JA:R05F9.13
JA:R05F9.3
JA:R05F9.8
JA:R13H9.2
JA:R13H9.4
JA:T13F2.10
JA:T13F2.11
JA:Y4C6A.c
JA:Y50E8.b
JA:ZK1248.17
JA:ZK1248.6
JA:ZK1251.6
JA:ZK354.1
JA:ZK354.11
JA:ZK354.4
JA:ZK354.5
JA:ZK546.3
JA:ZK546.6
JA:C33F10.9
[cgc5655]:C04G2.4
[cgc5655]:daf-2:R05F9.8
[cgc5655]:F32B6.6
[cgc5655]:R05F9.8
[cgc5655]:tph-1:R05F9.8
[cgc5655]:tub-1:R05F9.8
Simmer:ZK546.6:Repeat_a
Simmer:ZK546.6:Repeat_b
Simmer:ZK546.6:Screen
MV_SV:mv_C09B9.6
MV_SV:mv_C33F10.9
MV_SV:mv_C34F11.4
MV_SV:mv_C34F11.6
MV_SV:mv_F09C12.7
MV_SV:mv_F26G1.7
MV_SV:mv_F32B6.6
MV_SV:mv_F36H12.7
MV_SV:mv_K05F1.2
MV_SV:mv_K05F1.7
MV_SV:mv_R05F9.8
MV_SV:mv_Y59H11AM.d
MV_SV:mv_ZK1248.6
MV_SV:mv_ZK1251.6
MV_SV:mv_ZK354.4
MV_SV:mv_ZK546.6
Cenix:242-d2
Cenix:203-f3
Cenix:242-g2
Cenix:206-e1
Cenix:14-g4
Cenix:16-c9
Cenix:242-c6
Cenix:13-c7
Cenix:14-e7
Cenix:245-g4
JA:Y59E9_120.c
Expr_patternExpr3417
Reference (5)
MethodGene