Gene: F26G1.7
F26G1.7 | SMap | S_parent | Sequence | F26G1 | ||
---|---|---|---|---|---|---|
Chromosome | II | |||||
Identity (5) | ||||||
Gene_info | Gene_class | msp | ||||
Phenotype (2) | ||||||
GO_term | GO:0005198 | IEA | Inferred_automatically | |||
Structured_description | Provisional_description | msp-3 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-3 is similar in nucleotide sequence to the msp genes from the nematode Onchocerca volvulus; the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP proteins assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | Paper_evidence (5) | |||
Curator_confirmed | WBPerson324 | |||||
Date_last_updated | 26 Apr 2005 00:00:00 | |||||
Concise_description | msp-3 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-3 is similar in nucleotide sequence to the msp genes from the nematode Onchocerca volvulus; the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP proteins assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | |||||
Molecular_info (4) | ||||||
Experimental_info | RNAi_result | Cenix:246-b8 | ||||
JA:F26G1.7 | ||||||
WB_RNAi_result (69) | ||||||
Expr_pattern | Expr3417 | |||||
Reference (5) | ||||||
Method | Gene |