RNAiDB Tree View

Gene: F26H9.7

F26H9.7	SMap	S_parent	Sequence	F26H9
	Chromosome	I
	Identity (5)
	Gene_info	Gene_class	uev
		GO_term	GO:0008642	IEA	Inferred_automatically
			GO:0006464	IEA	Inferred_automatically
			GO:0006512	IEA	Inferred_automatically
		Structured_description	Provisional_description	uev-3 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; as loss of UEV-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UEV-3 in C. elegans development and/or behavior is not yet known; based on similarity to Saccharomyces cerevisiae and human proteins, however, UEV-3 may play a role in cell cycle control or response to stress or DNA damage.	Paper_evidence	WBPaper00005337
					Person_evidence	WBPerson1843
					Curator_confirmed	WBPerson1843
					Date_last_updated	17 Jun 2004 00:00:00
			Concise_description	uev-3 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; as loss of UEV-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UEV-3 in C. elegans development and/or behavior is not yet known; based on similarity to Saccharomyces cerevisiae and human proteins, however, UEV-3 may play a role in cell cycle control or response to stress or DNA damage.
	Molecular_info (5)
	Experimental_info	RNAi_result	Cenix:161-h2
			JA:F26H9.7
		WB_RNAi_result	JA:F26H9.7
			MV_SV:mv_F26H9.7
			Cenix:161-h2
	Reference	WBPaper00005337
	Remark	Sequence connection from [Jones D, Crowe E, Stevens TA, Candido EPM], 02/06/10 krb
	Method	Gene