RNAiDB Tree View

Gene: F29B9.6

F29B9.6	SMap	S_parent	Sequence	F29B9
	Chromosome	IV
	Identity (5)
	Gene_info	Gene_class	ubc
		GO_term	GO:0008642	IEA	Inferred_automatically
			GO:0006464	IEA	Inferred_automatically
			GO:0006512	IEA	Inferred_automatically
		Contained_in_operon	CEOP4128
		Structured_description	Provisional_description	ubc-9 encodes an E2 ubiquitin-conjugating enzyme orthologous to Saccharomyces cerevisiae Ubc9p, which mediates the covalent attachment of the small ubiquitin-related modifier (SUMO) to various substrates including Ran-GAP1 and p53; UBC-9 activity is required for several developmental processes including embryogenesis, larval development, vulval development, posterior morphogenesis, and the DNA damage response (both DNA repair and DNA damage checkpoint function); UBC-9 interacts with LIN-1, an ETS-domain-containing transcription factor that negatively regulates vulval development, and with RAD-51, the C. elegans RecA homolog that is required for DNA repair; the expression pattern and subcellular localization of UBC-9 are not yet known.	Paper_evidence	WBPaper00005039
						WBPaper00005337
						WBPaper00012383
					Person_evidence	WBPerson1843
					Curator_confirmed	WBPerson1843
					Date_last_updated	17 Jun 2004 00:00:00
			Concise_description	ubc-9 encodes an E2 ubiquitin-conjugating enzyme orthologous to Saccharomyces cerevisiae Ubc9p, which mediates the covalent attachment of the small ubiquitin-related modifier (SUMO) to various substrates including Ran-GAP1 and p53; UBC-9 activity is required for several developmental processes including embryogenesis, larval development, vulval development, posterior morphogenesis, and the DNA damage response (both DNA repair and DNA damage checkpoint function); UBC-9 interacts with LIN-1, an ETS-domain-containing transcription factor that negatively regulates vulval development, and with RAD-51, the C. elegans RecA homolog that is required for DNA repair; the expression pattern and subcellular localization of UBC-9 are not yet known.
	Molecular_info (6)
	Experimental_info	RNAi_result (5)
		WB_RNAi_result (5)
		Y2H_target	Y2H003408
		Interaction	WBInteraction0003898
	Reference (10)
	Remark	Sequence connection from [Jones D, Crowe E, Stevens TA, Candido EPM], 02/06/10 krb.
	Method	Gene