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Gene: F31E3.5   

F31E3.5SMapS_parentSequenceF31E3
ChromosomeIII
Identity (5)
Gene_info Gene_classeft
Allele q145 Inferred_automaticallyFrom strain object: JK1774
ar229 Paper_evidenceWBPaper00024924
Phenotype [C.elegansII] NMK. Encodes 463 aa protein with 83% identity to EF1alpha. eft-3:lacZ fusion expressed widely, but not in intestine or body wall muscle. [FK]
[C.elegansII] q145 : sterile, no germ line proliferation in hermaphrodites or males; about 3 undifferentiated germ cells per gonad arm. No somatic defects. OA4: q156, q171, q363, q456 (all similar). [JK]
[Kadyk LC] Homozygous q145 adults have germ lines with very few cells and no differentiated gametes, no somatic defects, hermaphrodites and males similarly affected. More proliferations at 25C, still sterile. Similar, slightly weaker phenotype in q145/sDf127. OA4: q156 possibly stronger allele.
StrainJK1774
GO_term (5)
Structured_description Provisional_description eft-3 encodes a translation elongation factor 1-alpha homolog that is required for embryonic viability, fertility, and germline maintenance; the EFT-3 protein sequence is encoded both by eft-3 (F31E3.5) itself but also by R03G5.1. Paper_evidence WBPaper00004313
WBPaper00004403
WBPaper00004651
Person_evidenceWBPerson567
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Paralogs are encoded by H19N07.1, K07A12.4, and other genes.
eft-3 expression is unaffected by smg mutations (unlike other translation-related genes such as rpl-3, rpl-7, rpl-10, or rpl-12.
Concise_descriptioneft-3 encodes a translation elongation factor 1-alpha homolog that is required for embryonic viability, fertility, and germline maintenance; the EFT-3 protein sequence is encoded both by eft-3 (F31E3.5) itself but also by R03G5.1.
Molecular_info (5)
Experimental_info RNAi_result (5)
WB_RNAi_result (11)
Expr_pattern Expr556
Expr5573
Reference (16)
MethodGene