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Gene: F32D1.1 
| F32D1.1 | SMap | S_parent | Sequence | SUPERLINK_RW5 | ||
|---|---|---|---|---|---|---|
| Chromosome | V | |||||
| Identity (5) | ||||||
| Gene_info | Allele (5) | |||||
| GO_term | GO:0000166 | IEA | Inferred_automatically | |||
| GO:0017111 | IEA | Inferred_automatically | ||||
| GO:0005524 | IEA | Inferred_automatically | ||||
| Contained_in_operon | CEOP5052 | |||||
| Structured_description | Provisional_description | F32D1.1 encodes an homolog of human SPASTIN (OMIM:604277, mutated in spastic paraplegia), FIDGETIN (OMIM:605295, mutated in fidget mice), and FIDGETIN-LIKE-1, and of Drosophila SPASTIN; recombinant F32D1.1 protein has N-ethylmaleimide-sensitive ATPase activity in vitro, which is strongly dependent on the C368 residue immediately C-terminal to its Walker A motif; F32D1.1 is required for persistence of the germline in RNAi assays. | Paper_evidence | WBPaper00024642 | ||
| WBPaper00025054 | ||||||
| Curator_confirmed | WBPerson567 | |||||
| Date_last_updated | 18 Jul 2005 00:00:00 | |||||
| Concise_description | F32D1.1 encodes an homolog of human SPASTIN (OMIM:604277, mutated in spastic paraplegia), FIDGETIN (OMIM:605295, mutated in fidget mice), and FIDGETIN-LIKE-1, and of Drosophila SPASTIN; recombinant F32D1.1 protein has N-ethylmaleimide-sensitive ATPase activity in vitro, which is strongly dependent on the C368 residue immediately C-terminal to its Walker A motif; F32D1.1 is required for persistence of the germline in RNAi assays. | |||||
| Molecular_info (5) | ||||||
| Experimental_info | RNAi_result | Cenix:119-b9 | ||||
| WB_RNAi_result | MV_SV:mv_F32D1.1 | |||||
| Cenix:119-b9 | ||||||
| Y2H_bait (6) | ||||||
| Y2H_target (5) | ||||||
| Method | Gene |
