Gene: F32D1.1
F32D1.1 | SMap | S_parent | Sequence | SUPERLINK_RW5 | ||
---|---|---|---|---|---|---|
Chromosome | V | |||||
Identity (5) | ||||||
Gene_info | Allele (5) | |||||
GO_term | GO:0000166 | IEA | Inferred_automatically | |||
GO:0017111 | IEA | Inferred_automatically | ||||
GO:0005524 | IEA | Inferred_automatically | ||||
Contained_in_operon | CEOP5052 | |||||
Structured_description | Provisional_description | F32D1.1 encodes an homolog of human SPASTIN (OMIM:604277, mutated in spastic paraplegia), FIDGETIN (OMIM:605295, mutated in fidget mice), and FIDGETIN-LIKE-1, and of Drosophila SPASTIN; recombinant F32D1.1 protein has N-ethylmaleimide-sensitive ATPase activity in vitro, which is strongly dependent on the C368 residue immediately C-terminal to its Walker A motif; F32D1.1 is required for persistence of the germline in RNAi assays. | Paper_evidence | WBPaper00024642 | ||
WBPaper00025054 | ||||||
Curator_confirmed | WBPerson567 | |||||
Date_last_updated | 18 Jul 2005 00:00:00 | |||||
Concise_description | F32D1.1 encodes an homolog of human SPASTIN (OMIM:604277, mutated in spastic paraplegia), FIDGETIN (OMIM:605295, mutated in fidget mice), and FIDGETIN-LIKE-1, and of Drosophila SPASTIN; recombinant F32D1.1 protein has N-ethylmaleimide-sensitive ATPase activity in vitro, which is strongly dependent on the C368 residue immediately C-terminal to its Walker A motif; F32D1.1 is required for persistence of the germline in RNAi assays. | |||||
Molecular_info (5) | ||||||
Experimental_info | RNAi_result | Cenix:119-b9 | ||||
WB_RNAi_result (2) | ||||||
Y2H_bait (6) | ||||||
Y2H_target (5) | ||||||
Method | Gene |