F33H1.2 | SMap | S_parent | Sequence | F33H1
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| Chromosome | II |
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Identity (5)
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Gene_info
| Gene_class | gpd
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| | Phenotype | [C.elegansII] NMK. Encodes glyceraldehyde-3-phosphate-dehydrogenase, minor isozyme (GAPDHase-1),ubiquitous, predominant expression in embryo; sequence closest to gpd-1. [Barrios et al. 1989; HH] |
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GO_term (6)
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Structured_description
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Provisional_description
| gpd-4 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-4 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; GPD-4 is required for embryonic and larval development; in C. elegans, GPD-4 and GPD-1 constitute the minor GAPDH isoenzymes and are expressed primarily in embryos, in all cell types. |
Paper_evidence
| WBPaper00000730
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| | | | | | WBPaper00001143
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| | | | | Person_evidence | WBPerson1843
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| | | | | Curator_confirmed | WBPerson1843
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| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | | GPD-4 and GPD-1 are nearly identical, exhibiting 99% identity at the amino acid level. |
| | | Concise_description | gpd-4 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-4 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; GPD-4 is required for embryonic and larval development; in C. elegans, GPD-4 and GPD-1 constitute the minor GAPDH isoenzymes and are expressed primarily in embryos, in all cell types. |
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Molecular_info (6)
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Experimental_info
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RNAi_result (5)
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WB_RNAi_result (14)
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| | Expr_pattern | Expr778
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| | Y2H_target | Y2H006956
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Reference (9)
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| Method | Gene
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