Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 

Gene: F36H12.6   

F36H12.6SMapS_parentSequenceF36H12
ChromosomeIV
Identity (5)
Gene_info Gene_classmsp
Phenotype[C.elegansII] NMK. Encodes MSP (16kD); msp-113 cluster. [Ward et al. (1988); BA]
Structured_description Provisional_descriptionmsp-52 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. Paper_evidence WBPaper00001023
WBPaper00002143
WBPaper00004591
WBPaper00005670
Curator_confirmedWBPerson324
Date_last_updated31 Mar 2005 00:00:00
Concise_descriptionmsp-52 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
Molecular_info Corresponding_pseudogeneF36H12.6
Corresponding_PCR_product (44)
Corresponding_RNAi_reagent mv_ZK354.4
sjj_ZK354.11
sjj_R05F9.8
Cenix:14-e7
sjj_F32B6.6
Cenix:13-d1
sjj_R13H9.2
sjj_ZK354.1
yk381d1
sjj_F36H12.7
sjj_F58A6.8
sjj_R05F9.3
Cenix:16-c9
sjj_ZK546.6
mv_F36H12.7
sjj_K07F5.3
Cenix:242-c6
sjj_Y59E9_120.c
Cenix:242-h2
sjj_K07F5.1
mv_C09B9.6
Cenix:211-g4
sjj_R05F9.13
sjj_T13F2.11
Cenix:247-a1
Cenix:205-e12
Cenix:14-g4
Cenix:245-g4
mv_ZK546.6
sjj_Y4C6A.c
sjj_T13F2.10
Cenix:13-f11
sjj_K07F5.2
Cenix:13-d7
yk384g8
sjj_R13H9.4
mv_R05F9.8
sjj_C09B9.6
yk370d1
sjj_ZK354.5
mv_F32B6.6
Cenix:242-g2
Cenix:242-g7
sjj_ZK354.4
Experimental_info WB_RNAi_result (71)
Expr_patternExpr3417
Reference WBPaper00001023
WBPaper00015440
Remarkpseudogene annotation in sequence. [sdm 05/00]
MethodGene