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Gene: F36H12.7 
| F36H12.7 | SMap | S_parent | Sequence | F36H12 | ||
|---|---|---|---|---|---|---|
| Chromosome | IV | |||||
| Identity (5) | ||||||
| Gene_info | Gene_class | msp | ||||
| Phenotype | [C.elegansII] NMK. Encodes MSP (16kD); msp-113 cluster. [Ward et al. (1988); BA] | |||||
| GO_term | GO:0005198 | IEA | Inferred_automatically | |||
| Structured_description | Provisional_description | msp-19 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-19 has a homolog in C. briggsae as predicted by the Wobble Aware Bulk Aligner (WABA); the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | Paper_evidence | WBPaper00001023 | ||
| WBPaper00002143 | ||||||
| WBPaper00004280 | ||||||
| WBPaper00004591 | ||||||
| WBPaper00005670 | ||||||
| Curator_confirmed | WBPerson324 | |||||
| Date_last_updated | 26 Apr 2005 00:00:00 | |||||
| Concise_description | msp-19 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-19 has a homolog in C. briggsae as predicted by the Wobble Aware Bulk Aligner (WABA); the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | |||||
| Molecular_info | Corresponding_CDS | F36H12.7 | ||||
| Corresponding_protein | WP:CE02806 | |||||
| Corresponding_PCR_product (58) | ||||||
| Corresponding_RNAi_reagent | Cenix:242-h2 | |||||
| sjj_F36H12.7 | ||||||
| sjj_C04G2.4 | ||||||
| mv_ZK354.4 | ||||||
| sjj_ZK354.11 | ||||||
| sjj_R05F9.8 | ||||||
| Cenix:14-e7 | ||||||
| sjj_C34F11.4 | ||||||
| sjj_F32B6.6 | ||||||
| Cenix:203-f6 | ||||||
| Cenix:13-d1 | ||||||
| sjj_R13H9.2 | ||||||
| sjj_ZK354.1 | ||||||
| sjj_C34F11.6 | ||||||
| yk381d1 | ||||||
| mv_C34F11.4 | ||||||
| sjj_K08F4.8 | ||||||
| sjj_F58A6.8 | ||||||
| sjj_R05F9.3 | ||||||
| mv_ZK1248.6 | ||||||
| Cenix:16-c9 | ||||||
| sjj_ZK546.6 | ||||||
| Cenix:242-d2 | ||||||
| mv_F36H12.7 | ||||||
| mv_C34F11.6 | ||||||
| sjj_K07F5.3 | ||||||
| sjj_F26G1.7 | ||||||
| Cenix:246-b8 | ||||||
| sjj_ZK546.3 | ||||||
| yk380e3 | ||||||
| Cenix:13-c7 | ||||||
| Cenix:242-c6 | ||||||
| sjj_Y59E9_120.c | ||||||
| Cenix:206-e1 | ||||||
| Cenix:243-c6 | ||||||
| sjj_K07F5.1 | ||||||
| mv_C09B9.6 | ||||||
| mv_F26G1.7 | ||||||
| Cenix:211-g4 | ||||||
| sjj_R05F9.13 | ||||||
| sjj_T13F2.11 | ||||||
| Cenix:247-a1 | ||||||
| Cenix:205-e12 | ||||||
| Cenix:14-g4 | ||||||
| Cenix:245-g4 | ||||||
| mv_ZK546.6 | ||||||
| sjj_Y4C6A.c | ||||||
| sjj_T13F2.10 | ||||||
| Cenix:13-f11 | ||||||
| sjj_K07F5.2 | ||||||
| sjj_F09C12.7 | ||||||
| Cenix:13-d7 | ||||||
| yk384g8 | ||||||
| sjj_R13H9.4 | ||||||
| mv_R05F9.8 | ||||||
| sjj_ZK1248.6 | ||||||
| mv_Y59H11AM.d | ||||||
| sjj_C09B9.6 | ||||||
| yk386a12 | ||||||
| yk387c2 | ||||||
| yk370d1 | ||||||
| sjj_ZK354.5 | ||||||
| mv_K05F1.2 | ||||||
| mv_F32B6.6 | ||||||
| Cenix:242-g2 | ||||||
| Cenix:242-g7 | ||||||
| sjj_ZK354.4 | ||||||
| Experimental_info | RNAi_result | Cenix:242-h2 | ||||
| JA:F36H12.7 | ||||||
| WB_RNAi_result (72) | ||||||
| Expr_pattern | Expr3417 | |||||
| Reference | WBPaper00001023 | |||||
| WBPaper00001024 | ||||||
| WBPaper00015440 | ||||||
| WBPaper00024312 | ||||||
| Remark | removed from gmap IV 1.61 [jah/sdm 5/99 | |||||
| Method | Gene |
