[C.elegansII] e185 : about 50% longer than wildtype at all stages, markedly tapering tail and head; low penetrance tendency to form constriction behind head, may result in auto-decapitation. Eggs elongated.ES3. Male bursa elongated ME0. OA5: e43, e1820, n1130 etc. (some have stronger Lon phenotype than e185, all show some decapitation). [Brenner 1974; MT]
The lon-1 gene encodes a protein belonging to the PR-protein superfamily that is a target of DBL-1 (TGF-beta) signaling, and that regulates polyploidization and body length.
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