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Gene: F53B2.6 
| F53B2.6 | Evidence | CGC_data_submission | ||||
|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | SUPERLINK_CB_IV | |||
| Chromosome | IV | |||||
| Identity (5) | ||||||
| Gene_info | Gene_class | ham | ||||
| Allele (6) | ||||||
| Phenotype | [C.elegansII] n1438 : multiple HSN defects, Egl, Dyf; HSN and sister phasmid neuron PHB both abnormal; also disrupted asymmetry in other sister cells RID, ADE/ADA, ADL, ALN/PLM. OA1: n1810. Cloned: 1.8 kb RNA, encodes 414 aa novel protein. [Desai et al. 1988; Garriga and Stern 1994; NG; NH; MT] | |||||
| Strain | MT3551 | |||||
| GO_term (5) | ||||||
| Structured_description | Provisional_description | ham-1 encodes a novel protein with a winged helix DNA-binding motif; ham-1 is required for the asymmetric divisions of several neuroblasts in the developing embryo and may influence their spindle position; ham-1 mutations also exhibit HSN motor neuron migration defects; HAM-1 interacts with itself in a yeast two-hybrid screen and observations suggest that its multimerization is required for its proper localization; HAM-1 is cytoplasmic and is asymmetrically distributed to the posterior of the HSNPHB neuroblast. | Paper_evidence | WBPaper00001105 | ||
| WBPaper00002607 | ||||||
| WBPaper00019286 | ||||||
| Person_evidence | WBPerson324 | |||||
| Curator_confirmed | WBPerson324 | |||||
| Date_last_updated | 17 Jun 2004 00:00:00 | |||||
| Concise_description | ham-1 encodes a novel protein with a winged helix DNA-binding motif; ham-1 is required for the asymmetric divisions of several neuroblasts in the developing embryo and may influence their spindle position; ham-1 mutations also exhibit HSN motor neuron migration defects; HAM-1 interacts with itself in a yeast two-hybrid screen and observations suggest that its multimerization is required for its proper localization; HAM-1 is cytoplasmic and is asymmetrically distributed to the posterior of the HSNPHB neuroblast. | |||||
| Molecular_info (5) | ||||||
| Experimental_info | RNAi_result | Cenix:47-b11 | ||||
| JA:F53B2.6 | ||||||
| WB_RNAi_result | JA:F53B2.6 | |||||
| MV_SV:mv_F53B2.6 | ||||||
| Cenix:47-b11 | ||||||
| Expr_pattern | Expr1604 | |||||
| Expr3416 | ||||||
| Reference (30) | ||||||
| Remark | Previous connection to hap-1 (ZC395.7) was incorrect [030311 ck1] | |||||
| Method | Gene |
