F58B6.3 | SMap | S_parent | Sequence | F58B6
|
| Chromosome | III |
|
Identity (5)
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Gene_info
| Gene_class | par
|
| |
Allele
| e2030
|
| | | it5
| Inferred_automatically | From strain object: KK114 |
| | | it46
|
Inferred_automatically
| From strain object: JR1763 |
| | | | | From strain object: LV15 |
| | | | | From strain object: LV18 |
| | | | | From strain object: LV19 |
| | | lw32
|
| | | n17
|
| |
Phenotype
| it46ts mat : homozygous hermaphrodites produce 90% (16x) to 99% (25x) arrested embryos escapers sterile; abnormal early cleavages defective P granule localization. ES3 (progeny). NA4 (it5ts : weaker phenotype e2030 : grandchildless). |
| | | See also e2030 |
| | | [C.elegansII] it46ts,mat : homozygous hermaphrodites produce 90% (16C) to 99% (25C) arrested embryos, escapers sterile; abnormal early cleavages, both spindles transverse at 2nd cleavage (failure of P1 rotation), defective P granule localization. ES3 (progeny). OA7: it5ts (weaker phenotype), e2030 (Mes, grandchildless),it87 (weak),jb2, etc. All ts; temp shift indicates not needed after 2nd cleavage. Cloned: encodes predicted novel protein. Antibody staining indicates specific asymmetric cortical localizations in early blastomeres. [Cheng et al. 1995; KK] |
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Strain (5)
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GO_term (9)
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| | Contained_in_operon | CEOP3056
|
| |
Structured_description
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Provisional_description (6)
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| | | Concise_description | par-2 encodes a protein containing a C3HC4-type RING-finger, a specialized type of zinc-finger found in E3 ubiquitin ligase subunits; PAR-2 is required maternally for polarization of the C. elegans zygote along the anterior-posterior (A-P) axis and is asymmetrically localized to the posterior cortex of the one- and two-cell embryo via interdependent interactions with PAR-3, PAR-6, and PKC-3. |
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Molecular_info
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Corresponding_CDS
| F58B6.3a
|
| | | F58B6.3b
|
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Corresponding_protein
| WP:CE25917
|
| | | WP:CE31016
|
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Corresponding_PCR_product
| smd_F58B6.3
|
| | | smd_F58B6.3:2
|
| | | sjj_F58B6.3
|
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Corresponding_RNAi_reagent
| Cenix:179-b5
|
| | | Cenix:238-a3
|
| | | sjj_F58B6.3
|
| | | [cgc5199]:par-2
|
| | | yk325e4
|
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Experimental_info (5)
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Reference (178)
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| Method | Gene
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