Gene: F59A6.8
F59A6.8 | SMap | S_parent | Sequence | F59A6 | ||
---|---|---|---|---|---|---|
Chromosome | II | |||||
Identity (5) | ||||||
Gene_info | Gene_class | msp | ||||
Phenotype | [C.elegansII] NMK. Encodes MSP (16kD); near msp-152. [Ward et al. (1988); BA] | |||||
Structured_description | Provisional_description | msp-71 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | Paper_evidence | WBPaper00001023 | ||
WBPaper00002143 | ||||||
WBPaper00004591 | ||||||
WBPaper00005670 | ||||||
Curator_confirmed | WBPerson324 | |||||
Date_last_updated | 31 Mar 2005 00:00:00 | |||||
Concise_description | msp-71 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. | |||||
Molecular_info (3) | ||||||
Experimental_info | WB_RNAi_result (83) | |||||
Expr_pattern | Expr3417 | |||||
Reference | WBPaper00001023 | |||||
WBPaper00001024 | ||||||
Method | Gene |