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GO_term: GO:0000367
| GO:0000367 | Definition | Catalysis of the second transesterification reaction of U12-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins. | ||
|---|---|---|---|---|
| Term | 2nd U12-type spliceosomal transesterification activity | |||
| second U12-type spliceosomal transesterification activity | ||||
| Type | Molecular_function | |||
| Parent | Instance_of | GO:0000386 | ||
| Attributes_of | Index | Ancestor | GO:0003673 | |
| GO:0003674 | ||||
| GO:0015597 | ||||
| GO:0015596 | ||||
| GO:0003824 | ||||
| GO:0017020 | ||||
| GO:0016362 | ||||
| GO:0016951 | ||||
| GO:0004322 | ||||
| GO:0004323 | ||||
| GO:0000385 | ||||
| GO:0000386 | ||||
| GO:0000367 | ||||
| GO:0004004 | ||||
| GO:0017116 | ||||
| GO:0015407 | ||||
| GO:0008564 | ||||
| GO:0019119 | ||||
| GO:0018863 | ||||
| GO:0004656 | ||||
| GO:0008734 | ||||
| Descendent | GO:0000367 |
