GO_term: GO:0000367   

GO:0000367	Definition	Catalysis of the second transesterification reaction of U12-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins.
	Term (2)
	Type	Molecular_function
	Parent	Instance_of	GO:0000386
	Attributes_of	Index	Ancestor (21)
			Descendent	GO:0000367

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